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Modification of human hearing loss by plasma-membrane calcium pump PMCA2

BMC Bioinformatics 12 , 323 (2011)

Whereas GSNO was stable under the experimental conditions, peptide bond hydrolysis by GGT liberated S-nitrosocysteinylglycine which rapidly decomposed in a metal ion-dependent process

Mol Pharmacol 59:674683

While these studies highlight the potential of dual-action therapies, larger-scale clinical trials are necessary to confirm their safety and efficacy in diabetic populations