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Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) represent unique cases of infection-triggered brain autoimmunity

Eriodictyol significantly improves cognitive deficits by activating the Nrf2/HO-1 pathway to inhibit ferroptosis

Statistical Analysis All experiments were repeated independently at least three times unless stated otherwise

17 , 21 , 30 The trigeminal nerve originates from the pons of the brainstem, allowing it to be a potential target nerve for drug transport to the CNS

PFS was defined as the time from the start of pemetrexed-containing chemotherapy to earlier disease progression or death from any cause