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In the present work, we used a combination of computational biology, metabolomics and mouse genetics to investigate the overall metabolic effects of FH loss and, in particular, the possible outcomes of FH loss and oxidative stress

Per Serving: % Daily Value*

Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio

10.1038/nrneurol.2017.139 204 StoffelsJ

This is important for both research and clinical translation, as it shifts the focus from observing disease to understanding the biological pathways behind it