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Howlett 2014

Full-length T4 (43 amino acids, ~4,963 Da) contains the sequence Ac-SDKPDM A EIEKFDKSKLKKTETQ, placing methionine between residues 5 and 7

the antibodies of the invention stimulate EphA2 phosphorylation in the mouse cell lines including but not limited to CT26 and 4T1 at least about 10%, at least about 20%, at least about 30%, at least about 40%, at least about 50%, at least about 60%, at least about 70%, at least about 80%, or at least about 90%, at least about 100%, at least about 110%, at least about 130%, at least about 140%, at least about 150%, at least about 160%, or at least about 170% more than control antibodies as described herein

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Contaminants of emerging concern were removed by multiple treatment barriers including oxidation, biological degradation, and adsorption