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About 1-2% of people develop sensitivity

doi: 10.1089/gtmb.2012.0376

85 Mattioni MarchettiV.KraftovaL.FinianosM.SourenianT.HrabakJ.BitarI

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(2021) elucidated that cynaroside exerted antiproliferative effects by inhibiting the STAT3 pathway in human umbilical vein endothelial cells (HUVEC), and down-regulating the transcription of IL-1, IL-6 and TNF-, thereby exerting antioxidant and anti-inflammatory effects