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10.1016/j.prostaglandins.2014.10.006 103 McgowanT.MccueP.SharmaK

Not for Certain Individuals Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

However, TNBC cells often upregulate ferroptosis defence mechanisms such as GPX4, SLC7A11, and FSP1 as adaptive responses, creating a state of non-oncogene addiction to antioxidant pathways (9396)

In this context, the in vitro alkaline single cell gel electrophoresis assay (SCGE or comet assay) has gained some attention as a potentially valuable, and complementary tool to the classical Ames test and EAT for predicting genotoxicity of NAs

PMID 24009505