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Here we demonstrated that lipid droplets (LDs) participate in SARS-CoV2 infection favoring virus replication and heightening inflammatory mediator production

Key issues include standardization of manufacturing processes, ensuring biocompatibility, achieving long-term stability, and scaling up production

In this review, we synthesize current evidence on the epidemiological association and mechanistic interplay between periodontitis and PD, with particular emphasis on oral and gut microbiota, key periodontal pathogens, immune dysregulation, oxidative stress, ferroptosis, and shared modifiers such as diet and vitamin D