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Prog Histochem Cytochem 44(3):125172 Ponraj T, Vivek R, Paulpandi M, Rejeeth C, Nipun Babu V, Vimala K, Anand K, Sivaselvam S, Vasanthakumar A, Ponpandian N, Kannan S (2018) Mitochondrial dysfunction-induced apoptosis in breast carcinoma cells through a pH-dependent intracellular quercetin NDDS of PVPylated-TiO2NPs

elegans and mice showed that EGCG's transient inhibition of Complex I in the electron transport chain triggered an adaptive stress response (mitohormesis) that ultimately restored ATP levels, reduced reactive oxygen species below baseline, and significantly extended lifespan and physical fitness

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Finding the answers to these questions will open up broader prospects for the research on the mechanism of cuproptosis and its clinical applications