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The preclinical literature does not prominently describe heart rate elevation

As usual, the truth lives somewhere in the middle

J Mol Med 76: 581588

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In contrast to this, neuroticism turned out to be a significant predictor of CE use regarding only two of the drug types assessed here - alcohol and modafinil, a clear divergence from existing literature as neuroticism has been previously linked to CE use broadly (Sattler and Schunck, 2016)