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Nitric oxide system modulation: The peptide interacts with the nitric oxide pathway, which regulates blood flow, inflammation, and cellular signaling

Studies examining links between TB500 and integrin linked kinase suggest potential involvement in pathways related to cell adhesion, structural organization, and communication between cells and their surrounding matrix

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Additionally, it reported that survival rates correlated with dose escalation, alongside elevated levels of cytokines such as IFN, IL4, and IL-6 in the participants (Nemunaitis et al., 2006)