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Myc hepatoblasts cells were injected subcutaneously into the flask of female CD1- Foxn1 nu outbred immunodeficient mice (68 weeks of age, strain code: 086, homozygous, obtained from Charles River Laboratories) to evaluate the capacity of cells to generate tumors in vivo

This polymorphism was retrospectively found to be over-represented in patients developing hepatotoxicity following intentional paracetamol overdose [39]

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