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Other forms of Hyper-androgenic state in women include a predisposition to oily skin or seborrhea and excessive hair growth in unwanted body areas such as limbs or face, termed as Hirsutism

M1 phenotype acts as an indicator of the inflammatory phase by releasing inflammatory cytokines such as IL-1, TNF-

Neurovascular complex A term proposed in 2021 to emphasize the diverse functional modules (cellular components, ultrastructure and biological function) both along the arteriovenous axis and in different brain regions

Additionally, careful consideration must be taken regarding the method of delivery, as systemic administration of RNAi or ASOs could potentially act on -syn expressed in peripheral tissues

Nanomedicines address the shortcomings of conventional therapy, as evidenced by several preclinical and clinical investigations indicating site-specific drug delivery, reduced side effects, and better treatment outcome