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Thus, the lack of CYP3A4 modulation is unlikely due to low plasma concentrations, and since the experiments were conducted under steady-state conditions after 7 days of oral administration of fluconazole, it is also unlikely that locally insufficient concentrations are behind the present observations

To date, two species within the genus, Lactococcus lactis and Lactococcus chungangensis , have been reported for their protective effects against alcohol-induced liver injury

Although GSH may function as a dynamic determinant of intracellular copper bioavailability rather than merely a passive buffering pool (Fig