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109 Autophagy is a cellular mechanism evolutionarily conserved from yeast to mammals that involves the degradation of cellular materials such as damaged organelles, unwanted proteins or foreign pathogens by capturing them in a double-membrane structure termed the phagophore, which can subsequently develop into a mature autophagosome and fuse with lysosomes

Nevertheless, physicians should avoid presenting testosterone as primary treatment for depression or cognitive impairment, as improvements vary considerably among individuals

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