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Exposure of differentiated SH-SY5Y neuron-like cells to high concentrations ( 100 M) led to increased oxidative stress, altered sirtuins expression, and ultimately cell toxicity

In dogs supplemented with a combination of betaine and L-carnitine, cytokine release in the absence of stimulation was reduced in compared to the control

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[23] demonstrated that curcumin treatment led to a decrease in the expression of inflammatory mediators such as IL-6, IL-8, MCP-1, and ICAM-1 at both the mRNA and protein levels in patients with Graves orbitopathy