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Cai Y, Xiang Y, Dong H, et al

A product of lipid peroxidation, 4-hydroxynonenal, has been shown to induce apoptosis in neuroblastoma cells by elevating the levels of p53, p63 and p73 and p63 staining has been used as a marker for prostatic adenocarcinoma where lack of p63 staining indicates malignant prostatic adenocarcinoma [14,18]