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The synaptic connection can either get stronger, known as long term potentiation (LTP) 1,2 , or the connection can get weaker, known as long term depression (LTD) 1,2

A novel tensor component analysis method (TCAM) 35 , allowing to longitudinally represent the 3-week study as a single compressed dot per animal, revealed that targeting CD38 improved both physical and metabolic features in 5xFAD mice (Fig

While prolonged exposure to acute insults such as drugs or infection are capable of causing CKD, chronic conditions such as diabetes mellitus and hypertension are more commonly the cause (Mehdi 2009

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Since the cytosolic concentration of GSH in unstressed cultured astrocytes is around 8 mM (Dringen and Hamprecht 1998), any treatment that increases the GSH concentration will also accelerate astrocytic GSH export, as demonstrated by the preincubation of cultured astrocytes with compounds such as ammonium (Murthy et al