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MiR-199a-3p, miR-143-3p, miR-340-5p, let-7b-5p, miR-21-5p, miR-103a-3p, miR-17-5p, and miR-20a-5p were all found to be at lower levels

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IGF-1 LR3 and Glucose Metabolism Research In differentiated 3T3-L1 adipocytes, IGF-1 LR3 was used to investigate IGFBP-independent IGF-1R-mediated glucose uptake pathways, with research confirming that its effects on glucose transport are mediated directly through the IGF-1 receptor rather than through IGFBP modulation providing a clean experimental tool for dissecting receptor-specific metabolic signalling