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Unlike synthetic hydrogels that often require the addition of exogenous growth factors, TCM supramolecular hydrogels act as "bioactive scaffolds," where the building blocks themselves exert pharmacological effectssuch as anti-inflammatory or antimicrobial activitiesto accelerate tissue repair and regeneration

This differs from the injection, which is weekly

[Abstract]2022 Mar;9(8):e2104344

doi: 10.1021/acs.analchem.7b01006

[16] It has been shown that the steric and electronic properties of the NHC ligand used in these borenium catalysts is of great importance to catalytic activity: NHCs that were too bulky prevented intermolecular hydride delivery and ligands that were highly electron donating weakened the borenium cation's ability to act as a Lewis acid