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More fluid means fewer copper ions hitting any single area, and it brings pH and osmolality closer to the physiological range

J Braz Chem Soc 28(10):20212027

D-Nle-Tyr-Ile-NH(CH 2 ) 5 CONH 2 exhibited no detectable metabolism over 90 min in an in-vitro metabolism assay using rat liver microsomes (data not shown)