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Instead, raised levels may indicate: Liver disease (impaired B12 storage and release) Myeloproliferative disorders or certain leukaemias Renal impairment Recent B12 supplementation or injection Isolated high B12 is usually due to supplementation or binding-protein changes and should be assessed against clinical context and other tests

When You Might Actually Consider Refrigeration While we generally advise against it, there are specific scenarios where the fridge might cross your mind

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A recent investigation supports this assertion, revealing that a combination of genetic and acquired/environmental factors contribute to the ethnic differences in serum vitamin B12 levels [39]