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Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Detection of glutathione and Fe3+ Hg2+ ions in living cells with a water soluble fluorescent probe ScienceDirect Frontiers Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities Mechanisms of ferroptosis regulation. The classic GPX4 (glutathione Download Scientific Diagram Role of oxidative stress and endoplasmic reticulum stress in drug induced liver injury
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