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Marselli L, Thorne J, Dahiya S, Sgroi DC, Sharma A, Bonner-Weir S, et al

PMID: 306 TarneckiA

"Mold" includes fungal organisms, actinomycetes, mycobacteria, VOC, beta glucans - a highly diverse antigenic stimulation and trigger for the immune system

This immune remodeling translates to substantial therapeutic benefits, with combination approaches (TMZ+anti-PD-1) achieving complete responses in 38% of preclinical models compared to 8% with immunotherapy alone [132]