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Neurological symptoms may develop insidiously and include paraesthesia (pins and needles), numbness in hands or feet, difficulty walking, memory problems, mood changes, or cognitive impairment

Folate (vitamin B9) deficiency is another major cause of anemia [33]

The addition of Pro-Gly-Pro at the C-terminus is associated with increased metabolic stability and potential for central nervous system penetration

Some non-deficient folks may subjectively feel more energetic or in a better mood after getting stuck, but the shots probably dont confer any actual physiological benefit for them A B12 deficiency is difficult to diagnose