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In protein modification, glyoxal and MG act as potent glycating agents, generating lysine-derived adducts (CML and CEL residues), bis(lysyl) crosslinks (GOLD and MOLD), and AGEs (G-H1 and MG-H1)

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Integrating these approaches with conventional treatments such as phototherapy or topical corticosteroids may offer a comprehensive therapeutic strategy to manage vitiligo by protecting melanocytes from oxidative stress and ferroptosis (136)

Moreover, PT cells do not use glucose, as they get their energy mostly from fatty acid oxidation (Gerich et al., 1963)