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doi: 10.1016/j.ebiom.2022.104258 43 DollSFreitasFPShahRAldrovandiMda SilvaMCIngoldIet al

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Recently, Bcl-2 was demonstrated to prevent autophagy.[25] Because Beclin-1 can interact with Bcl-2/Bcl-xL by its Bcl-2-homology-3-only domain, some research groups consider that Bcl-2 will completely inhibit the binding of Beclin-1 and Vps34

54 On the other hand, the KD-induced KBs may result in (1) satiety, which limits food intake and facilitates weight loss