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Although the precise mechanism of itaconate-dependent microglia activation and regulation requires further studies, the application of the cell- and brain-penetrable form of itaconate, 4OI, holds promise as a potential therapeutic approach for HAND

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This innovative technology activates the body's stem cells and has been proven through multiple clinical studies and 20 years of development to offer numerous benefits, including improved wound healing, increased energy, deeper sleep, quick pain relief, and even a reduction in the signs of aging

doi: 10.1146/annurev.nutr.27.061406.093734 27

Published Safety Profiles What does the published research say about this compound's effects in biological systems