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Interventions First Responder (FR) Interventions Place the patient in a position of comfort, as permitted by clinical condition

Z Bahadoran, P Mirmiran, F Hosseinpanah, M Hedayati, S Hosseinpour-Niazi, F Azizi (2011)

In this way, the "liver filter" is skipped and the first-pass metabolism that usually occurs in the liver is avoided, which deactivates a large part of the Glutathione molecule, making it less functional and effective

When activated by bioactive compound treatment, Nrf2 translocates to the nucleus and induces the expression of its target genes to exert antioxidant responses

These strategies may offer new approaches to treatment, particularly when conventional treatments prove ineffective