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[,,,,,,,,,,,,,] The CX 3 CL1-CX 3 CR1 signaling mediates splenic reservoir monocytes to adhere in the lung vasculature, induces the expression of vascular endothelial growth factor (VEGF) in intravascular monocytes, and subsequently pulmonary angiogenesis, thus leading to the abnormal gas exchange

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[42] Non-parenchymal cells such as Kupffer cells, collagen-producing stellate cells, and leukocytes (i.e