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The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents

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For example, the HCA 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), an amino acid pyrolysis product formed when meat is cooked at high temperatures, is transformed to its conjugate metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3,2:4,5]imidazo[1,2-]pyrimidin-5-ium chloride (PhIP-M1) in a microbial process that requires glycerol 26

A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language

However, it was less, this could be a result of minor degradation active peak and/or evaporation of the solvents (diluent) in prepared solutions since they were sensitive to changes in stability