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SLC7A11 was identified as a druggable target downstream of the MCU-Nrf2 axis (Wang et al., 2022)

The metabolic fate and mode of excretion of the drug have not been elucidated (Padda & Derian, 2024)

"Compounded retatrutide" in the wild usually means research-grade rather than true pharmacy compounding

Naming brands at this early signal-detection stage implied a level of certainty the data did not support, and media coverage amplified the brand list while largely stripping away the caveats