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Imerslund-Grsbeck syndrome as a rare disorder should be considered within patients excluding insufficient dietary intake, who present with deficiency of Vitamin B12 and mild proteinuria from early childhood, genetic-related examinations are of great significance for precise diagnosis

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This means looking at why the patient is deficient, who they are, and how long they need treatment

however, cases of hypercobalaminemia in leukemia, autoimmune diseases, and pulmonary and renal dysfunction have also been observed (Andrs et al., 2013