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Moreover, MDD has been linked to characteristics commonly associated with aging, suggesting that it may contribute to a premature aging phenotype, particularly in older adults who are already at heightened risk [489, 495]

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DEVELOPMENTAL CHANGES OF ENZYMES ASSOCIATED WITH ENERGY METABOLISM AND THE SYNTHESIS OF SOME NEUROTRANSMITTERS IN DISCRETE AREAS OF HUMAN NEOCORTEX

The role of metabolism in cancer Cancer metabolism has been a focus of scientific research since the early 20th century, with Otto Warburgs pioneering work on aerobic glycolysis, often referred to as the Warburg effect. Warburg observed that cancer cells preferentially consume glucose and produce lactate, even in the presence of oxygenan inefficient way to generate ATP compared to oxidative phosphorylation (OXPHOS)

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