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Phase II study of sunitinib in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

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Ballatori N, Krance SM, Notenboom S, et al

Since VSRs are crucial for directing cargo proteins to protein storage vacuoles (PSVs) during seed development and mediating the targeting of newly synthesized proteinases to PSVs for seed germination 45 , we observed significant defects in the seeds of the snx1 mutant and the snx1/snx2a/snx2b triple mutant, as well as GEF mutants of RAB5 and RAB7, such as vps9a-2 and mon1/ccz1ab