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Deterioration of CD was classified according to the CD activity index (CDAI) (34), which is a composite scoring system based on selected clinical symptoms, such as the number of liquid stools, the severity of abdominal pain, general well-being, extraintestinal CD manifestations, abdominal mass, use of antidiarrheal drugs, as well as haematocrit and body weight

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One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer