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Luana Stanescu: Nothing to Disclose, Bin Zhang: Nothing to Disclose, Alexander Miethke: Mirum Pharmaceutical Inc: Grant/Research Support, Mirum Pharmaceutical Inc: Consultant, Ipsen: Speaking and Teaching, Jonathan Dillman: GE HealthCare: Grant/Research Support, Philips Healthcare: Grant/Research Support, Motilent: Grant/Research Support, Perspectum: Grant/Research Support, Andrew Trout: Siemens Healthineers: Funding to institution, GE Healthcare: Funding to institution, GE Healthcare: Expert review of images, Perspectum Inc: Funding to institution 2343 SPATIAL HETEROGENEITY OF LIVER STIFFNESS BY MR ELASTOGRAPHY IN PATIENTS WITH PRIMARY SCLEROSIS CHOLANGITIS DOES NOT ASSOCIATE WITH CLINICAL OUTCOMES Erick Cruz Grave 1 Connie Chan 1 Michael Corwin 1 Richard Dean 1 Sandeep Dhaliwal 1 Maryam Yazdanfar 1 Christopher Bowlus 1 , 1 University of California, Davis Background: Primary sclerosing cholangitis (PSC) is a cholestatic liver disease that progresses to cirrhosis and liver failure

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Short-term treatment with liraglutide lowered ANG II concentrations by 21% and limited sodium reabsorption in the proximal renal tubules