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Moreover, inhibition of ROS production at the source has gained attention, particularly through NOX (NADPH oxidase) inhibition

In the cochlea, the sensory organ of hearing, cisplatin-induced ototoxicity is thought to be initiated by its uptake into the sensory HCs (HCs), spiral ganglion neurons (SGNs), and/or stria vascularis (SV) cells 17,23

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Notably, DRP-104 demonstrates the ability to counter T cell exhaustion and enhance the functionality of both CD4 + and CD8 + T cells [188]

More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy involving antitumor antibiotics