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They observed that clinical symptoms of withdrawal disappeared or improved markedly and rapidly in 97% of inpatients with alcohol dependence and 87% of those with opiate dependence.19 Apart from headaches in a few, all patients tolerated the treatment well

doi: 10.1016/j.plaphy.2010.08.016 56 Gimenez-IbanezS.HannD

10.1186/1477-7525-6-12 Health Quality Life Outcomes 44 LarssonM

These gene expression changes partially persisted after the intervention, suggesting that light therapy can modulate molecular circadian rhythms in NS workers, underscoring the potential use of circadian gene markers as early indicators of intervention efficacy in occupational chrono-medicine 211