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29 In a double-blind, placebo-controlled trial of ashwagandha extract, 1200 mg per day for 30 days, levels of fasting blood glucose and serum triglycerides significantly improved in patients with schizophrenia and metabolic syndrome, while no improvements were seen in the placebo group

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Reverse transcription and quantitative PCR Cells were seeded in six-well dishes and treated with desired reagents

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Most researchers add 50-100mcg increments after establishing tolerance at lower doses