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ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances (14)

A discolored or damp vial should not be used

Furthermore, we provide first data that the GSH level in human neurons may be mediated by NMDAR activation since the protective effect of enhanced network activity could be blocked with an NMDAR antagonist APV, consistent with the previous report (Fig