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5 Overall considerations and future/putative therapies and immunotherapies for MB The MB is an aggressive tumor characterized by a relevant molecular and cellular heterogeneity The advances in genomic and transcriptomic have identified several subtypes within the four subgroups (52, 56, 65, 71, 74, 79, 88, 306)

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2024) discovered that downregulating the VEGFA/VEGFR2 signaling pathway decreased ovarian hyperemia and cyst formation in a letrozole-induced PCOS rat model, suggesting its therapeutic potential