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Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL

Lyophilization, or freeze-drying, removes water from the peptide, making it incredibly stable for shipping and long-term storage

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Overall, stem-celland immune-cellderived secretomes offer a multi-modal, low-immunogenic platform to subdue microglial pyroptosis, but rigorous optimization and head-to-head validation are essential before clinical translation