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In this study, we demonstrate that the CDK11 inhibitor OTS964 traps the spliceosome in a novel intermediate, with the NTR complex integrated but the NTC complex not associated

Bacterial or fungal contamination poses genuine safety risks and renders the peptide unsuitable for any application

Next, the DCF fluorescence intensity was measured using a GloMax microplate reader (Promega, MA, USA) at the excitation wavelength of 485 nm and the emission wavelength of 535 nm

Subcutaneous administration delivers the peptide directly into the interstitial space, where it can access the lymphatic system and enter circulation with minimal degradation

Luo YH, Chang LW, Lin P (2015) Metal-based nanoparticles and the immune system: activation, inflammation, and potential applications