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This was confirmed by AlphaFold predictions, suggesting how NS3h and NS5B could be recruited, through known cis-acting RNA elements, to the 3UTR, where a complex between NS3h, NS5B and the terminal stem-loop would be involved in priming () strand synthesis

doi: 10.1016/j.smim.2016.10.009 34 ONeillLAKishtonRJRathmellJ

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What sets it apart from earlier compounds in the same category is its selectivity: it triggers GH release without meaningfully raising cortisol, prolactin, or other hormones that older secretagogues like GHRP-2 and GHRP-6 tended to drag up

Also, it may be more relevant for extreme paracetamol toxicity in patients (3)