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A recent study conducted on mice models of PD established that the N-homocysteinylation of -SN enhances its aggregation potential and increases its neurotoxicity and that higher Hcy levels correlated with more severe -synuclein deposition within mouse brains (Zhou et al

Research has pointed toward taking too much B12 also leads to issues such as vitiligo (changes in skin color), atopic dermatitis (eczema), rosacea (both mild and severe), and even allergic reactions (topical and anaphylaxis)

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The upper phase of supernatant was split into three parts: 50 l was used for gas chromatography coupled to mass spectrometry (GCMS) experiments in the injection vial, 30 l was used for the short-chain fatty acid ultra-high performance liquid chromatography (UHPLC)MS method, and 50 l was used for other UHPLCMS experiments