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Not only is the hormone imbalance physically stressful, it is also associated with several other related mental/life imbalances

Notably, NPCs from ASD-DM exhibited a greater number of differentially expressed genes (DEGs) compared to TD-N (204 downregulated, 174 upregulated) relative to ASD-N (86 genes downregulated, 88 genes upregulated) (Supplementary Figure 3A-C), indicating a more pronounced transcriptomic shift in the ASD-DM neurophenotype