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CMS added the Medicare Advantage disenrollment period in 2020 to give beneficiaries another chance to switch without having to wait a full calendar year

conservative approach is to avoid co-administration Guideline support / no major guideline addresses this combination Why This Interaction Matters Apixaban is the most prescribed direct oral anticoagulant (DOAC) in the United States, with over 28 million dispensed prescriptions in 2023 according to FDA postmarket data

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limited data suggest a cytoprotective role in ischemic or toxininduced injury contexts