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The Annals of pharmacotherapy, 46(2), 240247

It's very safe

In Denmark, however, patients receive injections of 1 mg cyanocobalamin per week during the first month and every 3 months after that, or 1 mg hydroxycobalamin every other month.

But biologically, one of its most important roles is supporting energy production especially in high-demand organs like the brain

This study also suggested the protective effect NR supplementation had on alcohol-induced liver injury, whose mechanism could involve the gut microflora-bile acid axis