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The mechanism of phosphine poisoning is through the obstruction of cytochrome-c oxidase, which suppresses oxidative phosphorylation and cell death and finally a disruption happen in mitochondrial respiration

150 Notably, the IP knockout mice showed increased infarct size after heart reperfusion injury, while TAX2 receptor (TP) knockout had no effect

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equivalents EtOAc or EA Ethyl acetate Et Ethyl EtOH Ethanol Ex example GST glutathione S-transferase H Hydrogen HATU N,N,N,N-tetramethyl-0-(7-a/abenzotriazol- 1 - yl)uronium hexafluorophosphate Hex hexanes HIS histidine h or hr Hours i iso IPA isopropanol Hz hertz MHz megahertz HPLC High pressure liquid chromatography RP-HPLC Reverseohase Hieh Dressure liauid chromatoeraDhv HOBT 1 -Hydroxybenzotria/ole hydrate Lawesson's Reagent [2,4-bis(4-methoxyphenyl)- 1 ,3-dithia-2,4- diphosphetane-2-4-disufide LC liquid chromatography LCMS or LC/MS liquid chromatograph mass spectrometry LDA lithium diisopropylamide m-CPBA or MCPBA meta-chloroperbenzoic acid Me methyl MeOH methanol min

In H 2 O 2 -induced oxidative stress models, curcumin has been shown to promote autophagy, potentially via inhibition of the AMPK/mTOR pathway in granulosa cells (Xu G