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The association between reduced eGFR and atherosclerotic CVD and cardiovascular mortality has been repeatedly reported previously [12, 14, 17]

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To circumvent the high lability of Cys acyclic disulfides during NCL and to use Cys thiol as a redox switch for controlling protein assembly, embedding the Cys thiol in a cyclic dichalcogenide represents a feasible solution as such species are known to be significantly less oxidizing than their linear counterparts 16

dietary sources include oily fish, algae oil, and krill oil)

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